ABSTRACT
Since the outbreak of COVID-19, the severe acute respiratory syndrome coronavirus 2 genome is still mutating. Omicron, a recently emerging virus with a shorter incubation period, faster transmission speed, and stronger immune escape ability, is soaring worldwide and becoming the mainstream virus in the COVID-19 pandemic. It is especially critical for the governments, healthcare systems, and economic sectors to have an accurate estimate of the trend of this disaster. By using different mathematical approaches, including the classical susceptible-infected-recovered (SIR) model and its extensions, many investigators have tried to predict the outbreaks of COVID-19. In this study, we employed a novel model which is based upon the well-known susceptible-infected-removed (SIR) model with the time-delay and time-varying coefficients in our previous works. We aim to predict the evolution of the epidemics effectively in nine cities and provinces of China, including A City, B City, C City, D City, E City, F City, G City, H City and I Province. The results show it is effective to model the spread of the large-scale and sporadic COVID-19 induced by Omicron virus by the novel non-autonomous delayed SIR compartment model. The significance of this study is that it can provide the management department of epidemic control with theoretical references and subsequent evaluation of the prevention, control measures, and effects.